This report analyses the impact of extreme temperatures on respiratory mortality across 646 Brazilian municipalities from 2010 to 2020. Findings reveal a J-shaped exposure-response curve, with heat-related deaths dominating in tropical northern regions, whilst cold-related mortality predominates in the subtropical south, underscoring the need for region-specific climate adaptation policies.

This report examines the 34% of the global women's health gap caused by care delivery failures. Focusing on cardiovascular risk and perinatal depression, it outlines the CARE framework to standardise screening and referral pathways, demonstrating that preventative care investments yield a three- to six-fold return.

This report presents a comprehensive framework and toolkit to help governments and stakeholders manage extreme heat risk. It provides actionable guidance, a maturity assessment tool, and strategies to operationalise governance and develop effective heat action plans across multiple sectors and timescales.

Impax Asset Management reviews sustainability-driven trends shaping healthcare, highlighting AI-enabled productivity gains, regulatory pressures, and supply chain localisation. The report examines opportunities in healthcare equipment, life sciences and managed care, alongside risks from regulation, product liability, affordability concerns and geopolitical tensions.

McKinsey Health Institute (MHI) is a global health research institute embedded within McKinsey & Company. It produces public research, data tools and insights on population health, mental health, health systems and workforce productivity, supporting evidence-based decision-making across healthcare, policy and business.

Institute for Health Metrics and Evaluation (IHME) is an independent global health research institute based at University of Washington. IHME produces data, metrics and analysis on disease burden, mortality, risk factors and health systems, supporting evidence-based policy, planning and health impact assessment worldwide.

This report analyses the link between ESG integration and global investor returns, drawing on cross-regional data and sector comparisons. It assesses how environmental, social, and governance factors correlate with performance, highlighting variations across markets and asset classes. The study provides evidence-based insights on ESG’s financial materiality for investors worldwide.

Water Footprint Implementation supports companies and governments with water accounting, sustainability assessment and water-footprint compensation. A spin-off of Water Footprint Network research, it delivers actionable insights for ESG reporting, water stewardship, water-footprint benchmarking and tailored reduction strategies to enhance resilience, reduce risk and foster sustainable water management.

This report examines the barriers to bringing new antibiotics to market, highlighting funding gaps, regulatory uncertainty, and weak commercial incentives. It outlines policy solutions to improve access and development, aiming to address the growing threat of antimicrobial resistance (AMR) by supporting viable pathways for pharmaceutical innovation.

Replacing Animal Research is a UK charity dedicated to ending animal testing by promoting human-relevant, non-animal research methods. Through funding scientific projects, publishing the peer-reviewed journal ATLA, and engaging in education and policy advocacy, it aims to create a world where no animal suffers for science.

This report examines how environmental, social, and governance (ESG) factors are being adopted in venture capital. It outlines current practices, challenges, and industry-specific considerations, and highlights the need for tailored guidance, collaboration, and early-stage engagement to advance responsible investment across the venture capital ecosystem.

The report outlines how strategic investment can reduce animal testing in the health sector. It provides investors with guidance on promoting transparency, encouraging non-animal methods, and influencing regulation, while highlighting the risks of limited disclosure and misalignment with consumer concerns.

This study examines the visibility of climate-related disclosures in reports from 28 large Australian ASX50 firms during 2022. It finds that disclosures on physical climate risks are generally limited and superficial, whereas opportunities from the transition to a low-carbon economy are more prominently highlighted, indicating selective disclosure practices across sectors.

CCLA’s 2024 report outlines investor-led efforts to address modern slavery through corporate engagement, policy advocacy, and improved data. Key sectors include construction and agriculture. Progress was made via benchmarking and collaborative initiatives, though disclosure and remedy remain limited. EU legislation and stakeholder coordination are driving further momentum.

This report presents insights from 34 national ecosystems advancing impact investing. It highlights trends in policy, capital mobilisation, and transparency, showing governments and institutions integrating social and environmental outcomes into investment strategies. It tracks growth in green finance, outcome-based funding, and investment readiness across emerging and developed economies.

This report outlines how deforestation, particularly in tropical forests, is a key driver of biodiversity loss and climate change. It presents the risks to institutional investors—physical, transition, and systemic—and offers a framework to assess deforestation exposure in portfolios using nature-related data and metrics across sectors and geographies..